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Pharmacology, Chapter 2

Teacher: Lori Yarger
Across
Initial metabolism of some oral drugs as they are carried from the intestine to the liver by the portal circulatory system prior to reaching the systemic circulation for distributation to site of action
Reactions between living systems and durgs; drug actions on target cells and the resulting alterations in cellupar biochemical reactions and functions
Labatory measurement of the amount of a drug in the blood at a particular time
When drugs are altered from their original form into a new form by the body; also referred to as metabolism
Drug that produces effects similar to those produced by naturally occurring hormones, neurotransmitters, and other substances
Process that occurs from the time a drug enters the blood-stream to be circulated
Drug that inhibits cell function by occupying receptor sites
Down
Immune-mediated reaction to a drug
Drug movement through the body to reach sites of action, metabolism, and excretion
Toxic or damaging effect of a substance on the kidney; potentially serious because renal damage interferes with drug excretion, causing drug accumulation and increased adverse effects
Time required for the serum concentration of a drug to decrease by 50%; also called elimination half-life
Elimination of a drug from the body
Substance that relieves, prevents, or counteracts the effect of a poison