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RBC Morphology

Across
Includes malaria, babesia, spirochetes, and trypanosomes
Mouth shaped central pallor due to failure of Na+ K+ pumps
Aggregates of iron appear as blue granules in cytoplasm
Large and lavender in color, caused by remnant RNA
Variation in RBC shape
Caused by attempt to compensate for blood loss, remnant RNA makes fine coarse blue dots throughout cytoplasm
Condensation of hemoglobin C gives this cell a "Washington Monument" shaped crystal
Fragmented cells due to hemolysis
Pear shape cell due to extramedullary hematopoiesis
Small, darker solid RBC that lacks central pallor due to defect in cell membrane
Abnormal variation in cell size
Associated with Hgb C, hemoglobin is pushed due on side with a clear "flap" area
Cells with normal complement of hemoglobin
Down
Caused by abnormal hemoglobin S, cells appear in crescent form
Bullseye appearance due to increased membrane lipids caused liver disease or anemias
Large red blood cell due to DNA synthesis defect
Only seen on supravital stain, denatured hemoglobin occurs due to G6PD deficiency
Fine single or double thread loop of nuclear membrane remnant due to megaloblastic anemia
Small, dense nuclear remnant on periphery of cell, caused by busy bone marrow
Increased central pallor due to lack of hemoglobin
Spiny projections off of cell due to increased abnormal membrane lipids
Indicator of hemoglobin production problem, creates a smaller cell
Clustered cells, due to RBC antibody or cold agglutination
Cigar shaped cell due to defect in membrane